CAS No.: 147-24-0
EINECS:205-687-2
Assay: 99%
Moleular Formula: C17H22ClNO
Molecular Weight: 291.82
Appearance: White or White crystalline powder
Grade:Pharmaceutical Grade
Diphenhydramine is an antihistamine mainly used to treat allergies.It is also used for insomnia, symptoms of the common cold, tremor in parkinsonism, and nausea.It is used by mouth, injection into a vein, and injection into a muscle.Maximal effect is typically around two hours after a dose and effects can last for up to seven hours.
Medical Uses:Diphenhydramine is a first-generation antihistamine used to treat a number of conditions including allergic symptoms and itchiness, the common cold, insomnia, motion sickness, and extrapyramidal symptoms.Diphenhydramine also has local anesthetic properties, and has been used as such in people allergic to common local anesthetics such as lidocaine.
Allergies:Diphenhydramine is effective in treatment of allergies,it is the most commonly used antihistamine for acute allergic reactions in the emergency department.Topical formulations of diphenhydramine are available, including creams, lotions, gels, and sprays. These are used to relieve itching, and have the advantage of causing fewer systemic effects than oral forms.
Movement Disorders:Diphenhydramine is used to treat Parkinson's disease-like extrapyramidal symptoms caused by antipsychotics.
Sleep:Because of its sedative properties, diphenhydramine is widely used in nonprescription sleep aids for insomnia. The drug is an ingredient in several products sold as sleep aids, either alone or in combination with other ingredients such as acetaminophen (paracetamol). An example of the latter is Tylenol PM. Diphenhydramine can cause minor psychological dependence.Diphenhydramine can cause sedation and has also been used as an anxiolytic.
Nausea:Diphenhydramine also has antiemetic properties, which make it useful in treating the nausea that occurs in vertigo and motion sickness.
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