CAS No.: 53-41-8
EINECS:200-173-4
Molecular Formula: C19H30O2
Molecular Weight: 290.44
Assay: 99%
Melting Point: 181-184 centigrade
Appearance: White or white crystalline powder
Usage:Pharmaceutical
Androsterone, or 3α-hydroxy-5α-androstan-17-one, is an endogenous steroid hormone, neurosteroid, and putative prehormone. It is a weak androgen with a potency that is approximately 1/7th that of testosterone.In addition, it can be converted to dihydrotestosterone (DHT) from 3α-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase, bypassing conventional intermediates such as androstenedione and testosterone, and as such, can be considered to be a metabolic intermediate in its own right.Androsterone is also known to be an inhibitory androstane neurosteroid,acting as a positive allosteric modulator of the GABAA receptor,and possesses anticonvulsant effects.The unnatural enantiomer of androsterone is more potent as a positive allosteric modulator of GABAA receptors and as an anticonvulsant than the natural form. Androsterone's 3β-isomer is epiandrosterone, and its 5β-epimer is etiocholanolone.
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