High quality peptide powder GDF-8/steroidmisty@ycphar.com

Product Name:GDF-8
Alias:Growth Differentiation Factor 8
Purity : 95%
Specification:1mg/vial
Grade : Pharmaceutical Grade

Myostatin (also known as growth differentiation factor 8, abbreviated GDF-8) is a myokine, a protein produced and released by myocytes that acts on muscle cells' autocrine function to inhibit myogenesis: muscle cell growth and differentiation. In humans it is encoded by the MSTN gene.Myostatin is a secreted growth differentiation factor that is a member of the TGF beta protein family.

Myostatin (GDF-8) is a member of the transforming growth factor-beta (TGF-beta) superfamily that is highly expressed in skeletal muscle, and myostatin loss-of-function leads to doubling of skeletal muscle mass. Myostatin-deficient mice have been used as a model for studying muscle-bone interactions, and here we review the skeletal phenotype associated with altered myostatin signaling. It is now known that myostatin is a key regulator of mesenchymal stem cell proliferation and differentiation, and mice lacking the myostatin gene show decreased body fat and a generalized increase in bone density and strength. The increase in bone density is observed in most anatomical regions, including the limbs, spine, and jaw, and myostatin inhibitors have been observed to significantly increase bone formation. Myostatin is also expressed in the early phases of fracture healing, and myostatin deficiency leads to increased fracture callus size and strength. Together, these data suggest that myostatin has direct effects on the proliferation and differentiation of osteoprogenitor cells, and that myostatin antagonists and inhibitors are likely to enhance both muscle mass and bone strength.

High quality peptide powder IGF1 Human Des1-3/steroidmisty@ycphar.com

Product Name:IGF1 Human Des1-3
Alias:IGF1 Des1-3
Molecular formula: C319H501N91O96S7
Molecular Weight : 7371.4 
CAS number: 112603-35-7
Appearance : Fine White Lyophilized Powder
Purity : 98%
Specification:1mg/vial
Grade : Pharmaceutical Grade

IGF1 Des1-3 is a naturally occurring, endogenous protein, as well as drug, and truncated analogue of insulin-like growth factor 1 (IGF-1)IGF1 Des1-3 lacks the first three amino acids at the N-terminus of IGF-1 (for a total of 67 amino acids, relative to the 70 of IGF-1).As a result of this difference, it has considerably reduced binding to the insulin-like growth factor-binding proteins (IGFBPs) and enhanced potency (about 10-fold in vivo) relative to IGF-1.

IGF-1 DES

DES IGF-1 is the shorter version of the IGF-1 chain. It is five times more powerful than IGF-LR3 and ten (10) times more powerful than regular base IGF-1. The half-life for DES is about 20-30 minutes, which means this is a very delicate chain. Therefore, administration should only be done at the site where you want to see muscle growth. DES has the ability to stimulate muscle hyperplasia better than LR3. In simple terms, it's best used for site injections, rather than overall growth.

In addition, DES is known to bind to receptors that have been deformed by lactic acid, which is often present during workouts. This allows the DES to attach itself to a mutated receptor and signal tissue growth during training. DES can be used longer and more frequently than LR3.

Dosing and Injections

DES IGF-1 can be dosed at 50-150mcg multiple times a day (prior to training) into specific target areas. since DES has such a short half life (20-30 minutes), desensitization was not noticed at all . Injection sites should be localized; preferably, at the muscle group you want to grow. In simple terms, if you want to grow your biceps, inject IGF-1 DES right into your bicep.

High quality peptide powder Deslorelin acetate/steroidmisty@ycphar.com

Product Name:Deslorelin Acetate
Sequence : Glp-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt
Cas No. : 57773-65-6
Molecular Formula : C64H83N17O12
Molecular Weight : 1282.47
Purity (HPLC) : 99.0%min.
Appearance : White powder
Single Impurity (HPLC) : 0.5%max
Amino Acid Composition : ±10% of theoretical
Peptide Content (N%) : ≥80.0%
Water Content (Karl Fischer) : ≤8.0%
Acetate Content (HPIC) : ≤12.0%
MS (ESI) : Consistent
Mass Balance : 95.0~105.0%
Grade : Pharmaceutical Grade
Storage: Closed, below 2 ~ 8℃ preservation
Usage : Deslorelin is primarily used for the initial flare effect upon the pituitary, and its associated surge of LH secretion.

Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. It stops the production of sex hormones (testosterone and oestrogen).
Deslorelin Acetate is marketed by Peptech with the brand name Ovuplant. It is currently approved for use in veterinary medicine and is used to induce ovulation in mares as part of the artificial insemination process. It is also used to stabilize high-risk pregnancies, mainly of livestock. Unlike other GnRH agonists, which are mainly used to inhibit luteinizing hormone and follicle-stimulating hormone by their ultimate downregulation of the pituitary gland, Deslorelin is primarily used for the initial flare effect upon the pituitary, and its associated surge of LH secretion.

Application:

Deslorelin was successfully trialed in the US and was approved for veterinary use under certain circumstances. In Europe, it was approved for use in equine assisted reproduction.
It is also being trialed in humans to study its efficacy in treatment of breast cancer in women,and in treating precocious puberty and congenital adrenal hyperplasia in male and female children.