Showing posts with label Finasteride. Show all posts
Showing posts with label Finasteride. Show all posts

Friday, December 1, 2017

Hair Loss Treatment Dutasteride /steroidmisty@ycphar.com

Product Name: Dutasteride
Other name: Duagen; Avodart,Dutas
CAS register number: 164656-23-9
Molecular formula: C27H30F6N2O2
Molecular weight: 528.53
Melting point: 242°C~250°C
Assay: 99%
Appearance:White crystalline powder 
Grade:Pharmaceutical Grade

Dutasteride Effect

Dutasteride (trademark name Avodart) is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT). Used for benign prostatic hyperplasia; however, it increases the risk of erectile dysfunction and decreased sexual desire.

Dutasteride is useful for the symptoms of benign prostatic hyperplasia (BPH); colloquially known as an "enlarged prostate". In those who are being regularly screened 5-alpha-reductase inhibitor (finasteride and dutasteride) reduce the overall risk of being diagnosed with prostate cancer however there is insufficient data to determine if they have an effect on the risk of death and may increase the chance of more serious cases. 

When bodybuilders use anabolic-androgenic steroids, it can speed up head hair loss. This is due to increased testosterone hormones in the body. The more testosterone, the more conversion to DHT in the body. In addition, running DHT derivatives such as masteron, winstrol, or proviron will further increase DHT. To combat this, bodybuilders have experimented with 5a-reductase inhibitors, such as dutasteride, to protect their existing hair and even re-grow more. However, this can come at a price and a myriad of side effects.

Dosage and Half-Life

A dosage of 2.5mgs per day is a popular starting point among bodybuilders. Most guys are splitting the dose into AM/PM, but that’s not necessary. The half-life of dutasteride is very long - up to 5 weeks. So, you can dose it EOD (every other day) or longer if you wish.

Weight loss 2,4-Dinitrophenol/steroidmisty@ycphar.com

Product Name:2,4-Dinitrophenol Sodium Salt
Alias:Sodium 2,4-dinitrophenate
CAS NO.:1011-73-0
Molecular Formula:C6H3N2NaO5
Molecular Weight:206.09
Purity:99%
Appearance:Orange Yellow Powder
Grade:Pharmaceutical Grade

DNP is an extremely powerful and beyond controversial fat burning drug. There is no compound on earth that can burn fat at the rate of DNP; however, to say it is beyond dangerous is almost an understatement. DNP is so dangerous it can in fact kill you. No one can deny the fat loss power held by this compound is truly tremendous, but when we consider the risk there are very few if any we can recommend it too.

Effects of DNP

The effects of DNP are very simple and very straightforward, tremendous fat loss and loss of total bodyweight. So powerful, the effects of DNP can result in a full pound of body fat loss per day. Note we said a full pound of body fat, not merely weight but actual pure body fat. That is truly amazing and could easily result in twenty plus pounds of fat loss in only a few weeks, not to mention any other weight lost, i.e. water weight.

That’s it, pure fat loss, rapid and tremendous fat loss represents the full effects of DNP. The compound carries no additional traits that could be potentially desired by any human being. While sometimes labeled as a performance enhancing drug DNP carries no anabolic properties. The compound will not help the individual build muscle mass or enhance strength. The individual will not see his athletic performance enhanced; in fact, many would see it diminished as DNP can be extremely draining on energy levels. Further, due to the tremendous increase in body temperature, when we look at the side effects of DNP we will find extreme activity must be avoided when using the compound.

When looking at the effects of DNP in a performance setting, many are often curious about its fat loss power compared to other more commonly used medications. The two most commonly used fat loss aids in performance enhancement circles are undoubtedly Clenbuterol and Cytomel (T3), and both are highly effective. However, while we cannot recommend DNP and while both Clen and T3 are far safer, we cannot deny the truth. DNP is far more powerful and will lead to greater and more dramatic fat loss than both Clenbuterol and Cytomel combined. This is simply the truth; however, both Clenbuterol and Cytomel can easily be used without severe or even fatal consequences, but we cannot say the same for DNP. Absolutely, DNP can be used without it leading to your death, there are those that get away with it, but the overall risk is so great you are truly playing with fire. At Steroid.com our job is to simply give you the truth. When explaining and covering various hormones and compounds, our job is to tell you exactly what the hormones and compounds in question can do. It is not our job to insight fear, or to embellish risks that may be associated with a compound in question. Our job is to take a neutral stance and simply explain what a compound can do, the good and the bad and nothing more. But when it comes to DNP it truly is pure poison and that is not an embellished statement. Regardless, some of you will still try it and while some of you will have success others will face horrific consequences and that’s the truth.

Side Effects of DNP

There are not too many side effects of DNP use, but what does exist is tremendously damaging. Of the side effects of DNP the most concerning is death. We actually mean your heart stopping and you living no more. There have been numerous deaths reported due to DNP use over the years. Although the compound is no longer legitimately obtainable on the pharmaceutical market, death will still be a possible side effect for those who are able to find it.

Beyond death, the most common side effects of DNP use include dramatic insomnia, nausea and extreme sweating. When we refer to extreme sweating, a more accurate way to describe it would be sweating profusely. Many who have used DNP have reported ruining their mattress during periods of use due to the sweating being so intense. DNP is also well-known for causing cataracts, which in many cases ultimately leads to the individual going blind.

DNP can also have a strong, negative impact on white blood cell count by reducing the total count severely. This can have a disastrous effect on the individual’s immune system. You will be far more susceptible to viruses and infections when using DNP. It is also very common for those who use DNP to fall into a coma, which can very easily lead to an untimely death. So powerful is the compound and so great is the risk of death, reports have indicated that death can occur with only a few days of use. Talk about a risk and one that is not worth taking.

Anabolic steroids Lorcaserin hydrochloride/steroidmisty@ycphar.com

Product Name: Lorcaserin HCl
CAS: 846589-98-8
MF: C11H14ClNClH
MW: 232.1525
Appearance:White Powder
Grade:Pharmaceutical Grade

Lorcaserin, currently marketed under the trade name Belviq and previously Lorqess during development,is a weight-loss drug developed by Arena Pharmaceuticals. It has serotonergic properties and acts as an anorectic.

Lorcaserin is used long term for weight loss in those who are obese.BELVIQ is an FDA-approved prescription weight-loss medication that, when used with diet and exercise, can help some overweight adults with a weight-related medical problem, or obese adults, lose weight and keep it off.

Lorcaserin VS Orlistat

Lorcaserin is a selective 5-HT2C receptor agonist,and in vitro testing of the drug showed reasonable selectivity for 5-HT2C over other related targets. 5-HT2C receptors are located almost exclusively in the brain. The activation of 5-HT2C receptors in the hypothalamus is supposed to activate proopiomelanocortin (POMC) production and consequently promote weight loss through satiety.The safety and effectiveness was tested in the 3 clinical trials which nearly 8000 overweight or obese participants were involved.

Orlistat works by inhibiting gastric and pancreatic lipases, the enzymes that break down triglycerides in the intestine. When lipase activity is blocked, triglycerides from the diet are not hydrolyzed into absorbable free fatty acids, and instead are excreted unchanged. Only trace amounts of orlistat are absorbed systemically; the primary effect is local lipase inhibition within the GI tract after an oral dose. The primary route of elimination is through the feces. But for a part of stubborn obesity who get good appetite, the treatment effect is not ideal.

Anabolic weight loss steroids Dextromethorphan Hydrobromide/steroidmisty@ycphar.com

Product Name:Dextromethorphan Hydrobromide 
Alias: Romilar,dextromethorphan,Demorphine,Dormetan 
CAS No.: 125-69-9 
EINECS No.: 204-750-1 
MF: C18H26BrNO 
MW: 352.31 
Purity: 98.0% 
Appearance: White or kind of white crystalline powder
Grade:Pharmaceutical Grade

Dextromethorphan (DXM or DM) is an antitussive (cough suppressant) drug.  Dextromethorphan has also found other uses in medicine, ranging from pain relief to psychological applications. It is sold in syrup, tablet, spray, and lozenge forms. In its pure form, dextromethorphan occurs as a white powder.

DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist.DXM and its major metabolite, dextrorphan, also acts as an NMDA receptor antagonist at high doses, which produces effects similar to, yet distinct from, the dissociative states created by other dissociative anaesthetics such as ketamine and phencyclidine. As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of DXM.

DXM Effect

DXM has dissociative effects, somewhat similar to ketamine and PCP. The main effects are those of dissociation (separation of mind and body), which include:

Double vision and no perception of depth (eyes are not able to focus)
Altered kinesthetic sense (distorted perception of gravity and movements)
Overall reduction of external stimuli (loosens the connection between mind and body, can lead to out-of-body experiences)
Total loss of reality awareness (dissociative anaesthesia - at high doses)
Euphoria
Emotion amplification
Hallucinations (closed-eye visuals, vision trails and increased awareness of color, flanging of sound)
Music appreciation

Sex Ehancement Powder Flibanserin/steroidmisty@ycphar.com

Product Name:Flibanserin
CAS NO.:167933-07-5
Molecular Formula:C20H21F3N4O
Molecular Weight:390.40
Purity:99%
Grade:Pharmaceutical Grade
Appearance:White powder
Grade:Pharmaceutical Grade

Flibanserin,sold under the trade name Addyi, is a medication approved for the treatment of pre-menopausal women with hypoactive sexual desire disorder (HSDD).The medication increases the number of satisfying sexual events per month by about one half to one over placebo from a starting point of about two to three.

Flibanserin is used for hypoactive sexual desire disorder among women. Those receiving flibanserin report that the average number of times they had “satisfying sexual events” rose from 2.8 to 4.5 times a month. However, women receiving placebo reported also an increase of “satisfying sexual events” from 2.7 to 3.7 times a month. Evaluation of the overall improvement of their condition and whether the benefit was meaningful to the women, showed a significantly higher rate of a meaningful benefit in the flibanserin-treated people versus the placebo group.The onset of the flibanserin effect was seen from the first timepoint measured after 4 weeks of treatment and maintained throughout the treatment period.

The effectiveness of flibanserin was evaluated in three phase 3 clinical trials. Each of the three trials had two co-primary endpoints, one for satisfying sexual events (SSEs) and the other for sexual desire. Each of the 3 trials also had a secondary endpoint that measured distress related to sexual desire.

All three trials showed that flibanserin produced a statistically significant increase in the number of SSEs and reduced distress related to sexual desire.

The first two trials used an electronic diary to measure sexual desire, and did not find a statistically significant increase relative to women treated with a placebo. These two trials also measured sexual desire using the Female Sexual Function index (FSFI) as a secondary endpoint, and a statistically significant increase was observed using this latter measure. The FSFI was used as the co-primary endpoint for sexual desire in the third trial, and again showed a statistically significant increase.

Sex Ehancement Powder Finasteride/steroidmisty@ycphar.com

Product Name:Finasteride
Alias: Proscar,Propecia,fincompared toteride
CAS No: 98319-26-7
MF: C23H36N2O2
MW: 372.55
Purity: 99.68%
Appearance: Off-white crystalline powder.
Grade: Pharmaceutical Grade

Treatment of Enlarged Prostate Gland

Finasteride (Proscar) is a very potent type II 5a-reductase inhibitor, which prevents conversion of testosterone to dihydrotestosterone (DHT). DHT is a sex hormone. In addition, it is used for treatment of benign prostatic hyperplasia (BPH), which is the enlargement of the prostate.

Finasteride inhibits 4a-reductase, and as mentioned, will prevent testosterone conversion to DHT. Studies have shown it will reduce serum DHT levels by about 65-70%, and prostate DHT levels, by up to 90%. By blocking DHT production, finasteride reduces androgen activity on the scalp; and in the prostate reduces prostate volume, which improves BPH, and reduces risk of prostate cancer.

Prevent Hair Loss

Bodybuilders will want to inhibit this conversion as much as possible to preserve hair loss, which is why finasteride is used. This is especially true when using DHT derivative anabolic steroids. Finasteride does a good job at keeping existing hair, and in almost half of men it will help grow more hair.

Finasteride is used to treat male pattern hair loss (androgenetic alopecia) in men only.Treatment provides about 30% improvement in hair loss after six months of treatment, and effectiveness only persists as long as the drug is taken.Clinical studies suggest that, with Finasteride 1 mg/day, continuously taking it for 3 months or slightly long , users can have their hair regrow, after 1 year if continuous treatment, hair growth rate is up to 48%.

Finasteride Dosage

Bodybuilders will dose Finasteride at 1mg per day to preserve hair. This is usually done during their DHT cycles.


Anabolic Steroids Cycles & Stacks Steroid Cycles

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