Showing posts with label MK-2866. Show all posts
Showing posts with label MK-2866. Show all posts

Friday, December 1, 2017

Bodybuilding Raw Powder SR9011/steroidmisty@ycphar.com

Product Name:SR9011
CAS NO.:1379686-29-9
Molecular Formula:C23H31ClN4O3S
Molecular Weight:479.03524
Purity:99%
Appearance:White Powder
Grade:Pharmaceutical Grade
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV ERB α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice.

The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.

Bodybuilding Raw Powder Ostarine(MK-2866)/steroidmisty@ycphar.com

Product Name:Ostarine,Enobosarm
Alias:GTx-024,MK-2866
CAS NO.:841205-47-8
Molecular Formula:C19H14F3N3O3
Molecular Weight:389.3279696
Purity:99%
Appearance:White Powder
Grade:Pharmaceutical Grade
SARM
Ostarine is selective androgen receptor modulator(SARM) and a kind of white powder.Ostarine belongs to chemical raw material. It is also known as enobosarm. Ostarine (MK-2866) is a SARM developed by GTx for the prevention and treatment of muscle wasting. It may eventually be a medical prescription for the prevention of cachexia, atrophy and sarcopenia as well as for Hormone or Testosterone Replacement Therapy.

As a research chemical, Ostarine belongs to a class of chemicals know as SARMS or selective androgen receptor modulators. SARMS create selective anabolic activity at certain androgen receptors. In comparison to testosterone and other anabolic steroids, the advantage of SARMS, is they do not have androgenic activity in non-skeletal muscle tissues. Ostarine is effective in maintaining and increasing lean body mass.

Enobosarm (Ostarine, MK-2866, GTx-024) - affects both muscle and bone, intended mainly for osteoporosis but also general treatment for andropause and reversing muscle sarcopenia in the elderly and for cachexia in cancer patients.Nonsteroidal selective androgen receptor modulator (SARM) used in the treatment of osteoporosis and muscle wasting in animal models. A potential compound for the treatment of hypoactive sexual desire disorder.

Ostarine Use

Increasing lean mass gains
Enhancement for  strength
Bodybuiling exercise
Joint healing abilities
Hormone Anabolic raw material (even at doses as low as 3 mg)

For bodybuilding

Ostarine is the most anabolic of any SARMS, making its first and foremost use for wanting to gain lean muscle. The gains in total weight will not be comparable to bulking steroids, however the total gains will almost entirely be lean muscle.

For cutting

Ostarine would primarily fit into a cutting protocol for the maintenance of muscle mass while reducing calories. One of the most disheartening outcomes of cutting is the loss hard earned muscle mass. The drop in metabolic rate and hormone levels (T3, IGF, Testosterone etc) with the lack of calories is a perfect catabolic environment for loss of muscle tissue. As Ostarine has anabolic effects, the dieter can cut calories without having to worry about muscle or strength loss. Ostarine has also shown noticeable nutrient partitioning effects among users, another reason why it can be of great help when cutting.

For Recomping

Where Ostarine shines for recomping is in its nutrient partitioning benefits. Calories are taken from fat stores and calorie intake is fed to the muscle tissue. In fact many users report that Ostarine consumed at maintenance calories produces weight loss, while still getting increases in strength and muscle mass.

Ostarine shines in recomping due to its nutrient portioning results. Calorie is used to build muscle which helps in weight loss and enhancing muscle mass and strength. Suggested dosing is 12.5-25 mg for 4-8 weeks.

Anabolic Steroids Cycles & Stacks Steroid Cycles

An anabolic steroid cycles refers to the time frame anabolic steroids are being used. This time frame is often referred to as “On-Cycle.”...