Alias:Melatonin
CAS NO.:73-31-4
EINECS:200-797-7
Molecular Formula:C13H16N2O2
Molecular Weight:232.28
Appearnace:White Powder
Grade:Food Grade
Sleep Aid
The hormone melatonin plays a role in your natural sleep-wake cycle. Natural levels of melatonin in the blood are highest at night. Some research suggests that melatonin supplements taken at the right time might be helpful in treating jet lag or other sleep disorders that involve poor alignment of your natural biological clock with the night-day pattern around you. Melatonin might also reduce the time it takes to fall asleep - although this effect is typically mild.
Melatonin is a natural hormone made by your body's pineal (pih-knee-uhl) gland. This is a pea-sized gland located just above the middle of the brain. During the day the pineal is inactive. When the sun goes down and darkness occurs, the pineal is "turned on" by the SCN and begins to actively produce melatonin, which is released into the blood. Usually, this occurs around 9 pm. As a result, melatonin levels in the blood rise sharply and you begin to feel less alert. Sleep becomes more inviting. Melatonin levels in the blood stay elevated for about 12 hours - all through the night - before the light of a new day when they fall back to low daytime levels by about 9 am. Daytime levels of melatonin are barely detectable.
Melatonin might be more effective for other types of sleep issues, such as delayed sleep disorder or other sleep disorders affecting circadian rhythm.
Side Effect
The most common melatonin side effects include:
Daytime sleepiness
Headaches
Dizziness
Other, less common melatonin side effects might include abdominal discomfort, mild anxiety, irritability, confusion and short-lasting feelings of depression.
Dosage
A typical dose for treating insomnia is 0.3 milligrams (mg) to 5 mg of melatonin at bedtime. Different medical conditions, and people of different ages, will require different dosages of the medicine.
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