High quality peptide powder PT-141/steroidmisty@ycphar.com

Product Name:Bremelanotide,PT-141
Alias: Brmelanotice,BreMelanotide Acetate
CAS Registry Number: 189691-06-3
MF: C50H69N15O10
MW: 1040.17736
Appearance: White powder 
Purity:99%
Grade: Pharmceutical Grade 

Developed From Melanotan II

Bremelanotide or PT-141, a research chemical and peptide, belongs to the classification known as melanocyte stimulating hormones (MSH).  It is a hexapeptide analog of alpha-MSH, and was originally developed from the MSH Melanotan II, a peptide agent that was reviewed in trials for sunless tanning but, unexpectedly, resulted in sexual arousal and sexual spontaneous erections in nine of ten test subjects.

Bremelanotide is a compound under drug as a treatment for female and male sexual dysfunction, hemorrhagic shock and reperfusion injury. 

Treatment of Sexual Dysfunction

Bremelanotide or PT-141 is the generic term for a new research peptide for use in helping improve sexual dysfunction in men (erectile dysfunction or impotence) as well as helping improve sexual dysfunction in women (sexual arousal disorder). 

PT-141 is a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction.Bremelanotide, PT-141 does not act on the vascular system like the former compounds but it is known and has been shown to help increase sexual activity in both male and female mammals. Bremelanotide PT-141 allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation. 

Bremelanotide is a novel treatment that could potentially change the face of treating sexual disorders, not only because of its effectiveness due to a unique mode of action, but also due to its safety and the fact it works synergistically with other ED/SAD treatments.

Bremelanotide is effective in its potential to treat sexual desire disorders as well as disorders that affect physical arousal. Bremelanotide induces lordosis in animal subjects, a sign of physical preparation for copulation. In males, it does not stimulate the vascular aspect of the penis, but instead acts to stimulate the central nervous system primarily via dopamine receptor activity to increase sexual desire and also demonstrates functionality in treating purely physical manifestations of ED/SAD, likely through improved signalling.

Co-administration of PT-141 and Sildenafil 

Bremelanotide also offers potential as a low-dose concurrent treatment with low-dose sildenafil.

The erectile response induced by co-administration of PT-141 and sildenafil was significantly greater than the response elicited by administration of sildenafil alone. Co-administration of PT-141 and sildenafil was safe and well-tolerated and did not result in new adverse events or adverse events that were increased in frequency or severity compared with monotherapy. Co-administration of intranasal PT-141 and a phosphodiesterase type 5 inhibitor may constitute a treatment alternative for patients in whom higher doses of a single therapy are not effective or well tolerated.

High quality peptide powder Pralmorelin GHRP-2/steroidmisty@ycphar.com

Product Name:GHRP-2 (Pralmorelin),Growth Hormone Releasing Peptide-2
CAS: 158861-67-7
Molecular Formula: C42H50N8O5
Molecular Weight: 746.90
Purity (HPLC): 98.0%min.
Appearance: White powder
Single Impurity (HPLC): 1.0%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%): >80.0%
Water Content(Karl Fischer): <6.0%
Acetate Content (HPIC): <12.0%
MS(ESI): Consistent
Mass Balance: 95.0~105.0%
Grade : Pharmaceutical Grade
Storage: Closed, below 2 ~ 8℃ preservation
Usage : GHRP - 2 is a true hGH secretagogue, which help to promote lean body mass and reduce adiposity (fat). GHRP - 2 also has a protective effect on the liver and an anti-inflammatory effect.

Description:

GHRP - 2 is a true hGH secretagogue. Which means it stimulates the body’s own secretion of hGH as explained in the study below. Human Growth hormone has been shown in studies to promote lean body mass and reduce adiposity (fat). ‘The group compared ITT to stimulation with GH releasing peptide 2 (GHRP-2). The synthetic hexapeptide, also named pralmorelin, is derived from a metenkephalin peptide. It is the most potent of the family of synthetic GH stimuli known in humans and acts via the endogenous ghrelin receptor (12). As these receptors have been identified both in the hypothalamus and the pituitary, GHRP-2 action may not be restricted to the pituitary.It has been reported that growth hormone (GH)-releasing peptide-2 (GHRP-2), a ghrelin receptor agonist, has an anti-inflammatory effect.
GHRP-2 is short for Growth Hormone Releasing Peptide 2, which basically refers to an hgH secretagogue, according to some research studies on rats, it can effectively increase the amount of natural secretion of hgH in the test subjects body and secrete it while stimulating the pituitary gland at the same time. Since the test subjects body will end up producing more growth hormones this way, fat will be reduced while lean muscle mass is increased. Along with this, IGF-1 levels will increase, as well, along with the different hypothalamus functions

Application:

The half-life of GHRP-2 is quite short, though, with its peak occurring around 15 minutes after its administration or an hour later at the latest. Ideally, this therapy should be administered periodically everyday.
Similar to GHRP-6, GHRP-2 is its commercially synthesized form that can stimulate the growth hormone secretion much better and stimulate the PRL, cortisol and ACTH levels a little better. For ghrelin, on the other hand, it functions like a synthetic agonist that can connect with the secretagogue receptor of the growth hormone. GHRP-2 can also increase the levels of calcium ion influx and, in turn, release even more growth hormones.
Aside from that, some research has already been done proving how similar it is with the effectiveness of GRF, as well. As a matter of fact, it has proven to be much more potent compared to any other GH-releasing secretors known in the past, including GHRP-1 and GHRP-6. Because of this, this hormone is often used as a treatment for catabolic deficiencies and states nowadays.
GHRP-2 basically acts exactly like ghrelin. It can induce food consumption just like ghrelin and stimulate GH secretion, too. When infused, GHRP-2 makes the GH levels in the body increase a lot and it can induce cell cAMP secretion the way that GRF tends to, as well.
Aside from that, the supplements of GHRP-2 are known to be anti-inflammatory. However, its results tend to differ between research test subjects, depending on how each subject’s pituitary somatotrophs choose to respond based on the different receptor subtypes of GHRP overall.

Bodybuilding Peptide PT-141/Bodybuilding Peptide

CAS 189691-06-3 PT-141

Product Name:Bremelanotide,PT-141
Alias: Brmelanotice,BreMelanotide Acetate
CAS Registry Number: 189691-06-3
MF: C50H69N15O10
MW: 1040.17736
Appearance: White powder 
Purity:99%
Grade: Pharmceutical Grade 

Developed From Melanotan II

Bremelanotide or PT-141, a research chemical and peptide, belongs to the classification known as melanocyte stimulating hormones (MSH).  It is a hexapeptide analog of alpha-MSH, and was originally developed from the MSH Melanotan II, a peptide agent that was reviewed in trials for sunless tanning but, unexpectedly, resulted in sexual arousal and sexual spontaneous erections in nine of ten test subjects.

Bremelanotide is a compound under drug as a treatment for female and male sexual dysfunction, hemorrhagic shock and reperfusion injury. 

Treatment of Sexual Dysfunction

Bremelanotide or PT-141 is the generic term for a new research peptide for use in helping improve sexual dysfunction in men (erectile dysfunction or impotence) as well as helping improve sexual dysfunction in women (sexual arousal disorder). 

PT-141 is a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction.Bremelanotide, PT-141 does not act on the vascular system like the former compounds but it is known and has been shown to help increase sexual activity in both male and female mammals. Bremelanotide PT-141 allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation. 

Bremelanotide is a novel treatment that could potentially change the face of treating sexual disorders, not only because of its effectiveness due to a unique mode of action, but also due to its safety and the fact it works synergistically with other ED/SAD treatments.

Bremelanotide is effective in its potential to treat sexual desire disorders as well as disorders that affect physical arousal. Bremelanotide induces lordosis in animal subjects, a sign of physical preparation for copulation. In males, it does not stimulate the vascular aspect of the penis, but instead acts to stimulate the central nervous system primarily via dopamine receptor activity to increase sexual desire and also demonstrates functionality in treating purely physical manifestations of ED/SAD, likely through improved signalling.

Co-administration of PT-141 and Sildenafil 

Bremelanotide also offers potential as a low-dose concurrent treatment with low-dose sildenafil.

The erectile response induced by co-administration of PT-141 and sildenafil was significantly greater than the response elicited by administration of sildenafil alone. Co-administration of PT-141 and sildenafil was safe and well-tolerated and did not result in new adverse events or adverse events that were increased in frequency or severity compared with monotherapy. Co-administration of intranasal PT-141 and a phosphodiesterase type 5 inhibitor may constitute a treatment alternative for patients in whom higher doses of a single therapy are not effective or well tolerated.