High quality peptide powder Mechano Growth Factor,MGF/steroidmisty@ycphar.com

Product Name:Mechano Growth Factor,MGF
MF: C121H200N42O39
MW: 2888.16
Purity: 99%
Specification: 2mg/vial
Appearance: White Lyophilized Powder
Grade:Pharmarceutical Grade

2 kinds of MGF splice variants of IGF

Mechano Growth Factor (MGF) also known as IGF-1Ec is a growth factor/repair factor that is derived from exercised or damaged muscle tissue.  It’s called MGF as IGF-IEa is a bit of a mouthful and harder to identify amongst the other IGF variants.

IGF-1Ec:This is the first phase release igf splice variant and it appears to stimulate satellite cells into activation, This is the closest variant to synthetic MGF.When mechanical overload is introduced to a muscle (as by weight training), the IGF-1 gene released and is differentially spliced during the bodies response. Initially, it it is spliced to produce predominantly IGF-1Ec (called the MGF splice variant of IGF-1). This early splicing stimulates satellite cells into activation. Which in turn allows the activation of extra undamaged nuclei to grow new muscle fiber and tissue. The appearance of MGF also initiates the upregulation of new protein synthesis. 

IGF-1Ea:After this initial splicing of IGF-1 into MGF, production then switches towards producing a systemic release of IGF-1Ea from the liver, which also upregulates protein synthesis as well. It is the secondary release of igf from the liver, and its far less anabolic and shorter acting.

The expression of IGF-1 splice variants, over the course of the healing and regrowth phase of muscle repair is thought to be the primary anabolic mechanism by which the body produces new muscle. MGF is available as an injectable peptide, and it has been anecdotally shown that injecting it will cause a response in the area resulting in localized muscle growth.

MGF Benefits

MGF is a splice variant of the IGF gene which increases stem cell count in the muscle and allows for muscle fibers to fuse and mature. This is a process required for growth of adult muscle. Natural MGF is made locally and does not travel into the bloodstream. Synthetic MGF is water based and when administered intramuscularly, travels into the bloodstream. MGF is only stable in the blood stream for only a few minutes.

In bodybuilding this drug is used to accelerate muscle growth. Other effects of the drug include decrease of fat mass of the body, endurance increase, improvement of immune defenceand skin, bone strengthening, lowering of cholesterol level, accelerated recovery. Those who administered MGF declared that they experienced no side effects, which frequently occur with the use of other drugs for gaining body mass.

Muscle Repair Factor

When you train, what happens to your muscles is they break down, the cells are damaged, muscle tissue needs to be repaired and your body produces 2 forms of MGF splice variant.  The first initial release of the above mentioned number 1 variant from the liver helps muscle cell recovery, if there is no MGF then muscle cells die.

As muscle is a post-mitotic tissue and as such cell replacement is not a means of tissue repair, if the cells are not repaired they die and your muscles get smaller and weaker.  In muscle tissue, the pool of these stem cells is apparently replenished by the action of MGF, which is produced as a pulse following damage.

Now, with synthetic injections of MGF you can increase the pulse and so speed up recovery, and increase the muscle tissue cells by stimulating satellite cells into full maturity. In terms of dosages, 200mcg bi-laterally is the very best choice of dosing in muscles trained.

High quality peptide powder TB500/steroidmisty@ycphar.com

CAS 77591-33-4 TB500

Product Name:TB500,Thymosin beta 4 acetate
CAS:77591-33-4
Molecular Formula:C212H350N56O78S
Molecular Weight:4963.50
Specification:2mg/vial
Appearance : White to off-white crystalline powder or lumps
Grade:Pharmaceutical grade

TB500 is part of Thymosin beta 4 acetate

TB-500 is a synthetic fraction of the protein thymosin beta-4, which is present in virtually all human and animal cells. Thymosin beta-4 is a very large molecule. In fact, it is so large that it cannot fit entirely into the receptor. Different sections of the molecule have different activities. TB-500 is the part of thymosin beta-4 hormone which promotes the most useful effects (overall healing, repair, new blood and muscle cells). For medical applications it is more practical to use the TB-500 instead of the entire Thymosin Beta-4 protein.

Promote Healing

The main purpose of TB500 is to promote healing. It also promotes creation of new blood and muscle cells. The healing effects of TB-500 have been observed in tendons, ligaments, muscle, skin, heart, and the eyes. Thymosin beta-4 is naturally produced in higher concentration where tissue has been damaged. 

TB-500 is specifically designed to help deal with injured athletes and bodybuilders,it is an injectable peptide drug which can be used to promote healing, enhance range of motion in cases of injury, or reduce pain in case of injury by reducing inflammation.This peptide is also a very potent anti-inflamatory agent.

TB500 is a synthetic peptide that has been directly linked to recovery as it is plays a vital role in building new blood vessels, new small muscle tissue fibers, cell migration and blood cell reproduction.  If you are an injured athlete, all of these properties are something that becomes very desirable when looking to speed up the recovery process. 

Dosage and Usage

TB500 is distributed as a lyophilized powder that should be kept out of the light and in a cool dry place.  Reconstitution is done with bacteriostatic water or sodium chloride meant for injection.  Doses range from 2-2.5mg twice weekly for 4-6 weeks (some user have reported success in dosing higher up to 8mg a week but how much more effective this is yet to be seen) .  Beyond that, one to two monthly injections of 2-2.5mg of TB500 can be further utilized to maintain rapid recovery and flexibility in strained areas.

For optimal recovery, a combination of TB500 with MK-2866 (Ostarine) should be used.  This combination allows the healing benefits of SARMS and peptides to delivery maximum results.

Side Effects

The positive attributes of TB500 include blood vessel and cell differentiation, growth of new blood cells from pre-existing vessels in dermal tissue, decreased inflammation and increase in flexibility.  The flu like symptoms or lethargy/head rush associated with most peptides does not seem to be widely reported with TB500.  Everybody is different, so always follow the suggested dosing protocols and practice sterile injection techniques.  This will cut down on environmental side effects associated with injections.

Bodybuilding Peptide PT-141/Bodybuilding Peptide

CAS 189691-06-3 PT-141

Product Name:Bremelanotide,PT-141
Alias: Brmelanotice,BreMelanotide Acetate
CAS Registry Number: 189691-06-3
MF: C50H69N15O10
MW: 1040.17736
Appearance: White powder 
Purity:99%
Grade: Pharmceutical Grade 

Developed From Melanotan II

Bremelanotide or PT-141, a research chemical and peptide, belongs to the classification known as melanocyte stimulating hormones (MSH).  It is a hexapeptide analog of alpha-MSH, and was originally developed from the MSH Melanotan II, a peptide agent that was reviewed in trials for sunless tanning but, unexpectedly, resulted in sexual arousal and sexual spontaneous erections in nine of ten test subjects.

Bremelanotide is a compound under drug as a treatment for female and male sexual dysfunction, hemorrhagic shock and reperfusion injury. 

Treatment of Sexual Dysfunction

Bremelanotide or PT-141 is the generic term for a new research peptide for use in helping improve sexual dysfunction in men (erectile dysfunction or impotence) as well as helping improve sexual dysfunction in women (sexual arousal disorder). 

PT-141 is a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction.Bremelanotide, PT-141 does not act on the vascular system like the former compounds but it is known and has been shown to help increase sexual activity in both male and female mammals. Bremelanotide PT-141 allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation. 

Bremelanotide is a novel treatment that could potentially change the face of treating sexual disorders, not only because of its effectiveness due to a unique mode of action, but also due to its safety and the fact it works synergistically with other ED/SAD treatments.

Bremelanotide is effective in its potential to treat sexual desire disorders as well as disorders that affect physical arousal. Bremelanotide induces lordosis in animal subjects, a sign of physical preparation for copulation. In males, it does not stimulate the vascular aspect of the penis, but instead acts to stimulate the central nervous system primarily via dopamine receptor activity to increase sexual desire and also demonstrates functionality in treating purely physical manifestations of ED/SAD, likely through improved signalling.

Co-administration of PT-141 and Sildenafil 

Bremelanotide also offers potential as a low-dose concurrent treatment with low-dose sildenafil.

The erectile response induced by co-administration of PT-141 and sildenafil was significantly greater than the response elicited by administration of sildenafil alone. Co-administration of PT-141 and sildenafil was safe and well-tolerated and did not result in new adverse events or adverse events that were increased in frequency or severity compared with monotherapy. Co-administration of intranasal PT-141 and a phosphodiesterase type 5 inhibitor may constitute a treatment alternative for patients in whom higher doses of a single therapy are not effective or well tolerated.