High quality peptide powder TB500/steroidmisty@ycphar.com

CAS 77591-33-4 TB500

Product Name:TB500,Thymosin beta 4 acetate
CAS:77591-33-4
Molecular Formula:C212H350N56O78S
Molecular Weight:4963.50
Specification:2mg/vial
Appearance : White to off-white crystalline powder or lumps
Grade:Pharmaceutical grade

TB500 is part of Thymosin beta 4 acetate

TB-500 is a synthetic fraction of the protein thymosin beta-4, which is present in virtually all human and animal cells. Thymosin beta-4 is a very large molecule. In fact, it is so large that it cannot fit entirely into the receptor. Different sections of the molecule have different activities. TB-500 is the part of thymosin beta-4 hormone which promotes the most useful effects (overall healing, repair, new blood and muscle cells). For medical applications it is more practical to use the TB-500 instead of the entire Thymosin Beta-4 protein.

Promote Healing

The main purpose of TB500 is to promote healing. It also promotes creation of new blood and muscle cells. The healing effects of TB-500 have been observed in tendons, ligaments, muscle, skin, heart, and the eyes. Thymosin beta-4 is naturally produced in higher concentration where tissue has been damaged. 

TB-500 is specifically designed to help deal with injured athletes and bodybuilders,it is an injectable peptide drug which can be used to promote healing, enhance range of motion in cases of injury, or reduce pain in case of injury by reducing inflammation.This peptide is also a very potent anti-inflamatory agent.

TB500 is a synthetic peptide that has been directly linked to recovery as it is plays a vital role in building new blood vessels, new small muscle tissue fibers, cell migration and blood cell reproduction.  If you are an injured athlete, all of these properties are something that becomes very desirable when looking to speed up the recovery process. 

Dosage and Usage

TB500 is distributed as a lyophilized powder that should be kept out of the light and in a cool dry place.  Reconstitution is done with bacteriostatic water or sodium chloride meant for injection.  Doses range from 2-2.5mg twice weekly for 4-6 weeks (some user have reported success in dosing higher up to 8mg a week but how much more effective this is yet to be seen) .  Beyond that, one to two monthly injections of 2-2.5mg of TB500 can be further utilized to maintain rapid recovery and flexibility in strained areas.

For optimal recovery, a combination of TB500 with MK-2866 (Ostarine) should be used.  This combination allows the healing benefits of SARMS and peptides to delivery maximum results.

Side Effects

The positive attributes of TB500 include blood vessel and cell differentiation, growth of new blood cells from pre-existing vessels in dermal tissue, decreased inflammation and increase in flexibility.  The flu like symptoms or lethargy/head rush associated with most peptides does not seem to be widely reported with TB500.  Everybody is different, so always follow the suggested dosing protocols and practice sterile injection techniques.  This will cut down on environmental side effects associated with injections.

High quality peptide powder Selank/steroidmisty@ycphar.com

Product Name:Selank
Synonyms: Selanc
Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
Molar Mass: 751.8
Purity:98.71%
Specification:5mg/vial
Appearance:White Lyophilized Powder

Selank or selanc is a synthetic heptapeptide analog of the endogenous tetrapeptide tuftsin, with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. This synthetic variant of immunomodulatory tetrapeptide tuftsin possesses anxiolytic properties because of its mimic nature. Among this peptide's positive characteristics, are its ability to induce serotonin’s metabolic processes and affect the concentration of specific monoamine neurotransmitters. Some scientists believe that Selank possesses such modulatory feature as influencing expression of brain-derived neurotropic factor.

Neuropeptide Selank is a synthetic derivative of the human body's naturally produced tetrapeptide Tuftsin. It is a hexapeptide whith a wide range of uses. Selank is used as an anxiolytic in the therapy of anxiety and phobic disorders, including generalized anxiety. Its action is similar to that of mild benzodiazepins but without the sedative effects. As a selective anxiolytic with a nootropic component, Selank can be used as treatment of depression, fear and general anxiety. It also reduces phsychic tension. This neuropeptide has passed all phases of clinical trials and is now being prepared for registration and mass production. 

Selank is closely related to Semax, a hexapeptide previously invented by the same institute. Some consider Selank to be a more efficient alternative to Semax. 

Selank as a Nootropic 

Recreationally Selank is used to improve one's ability to focus and concentrate, reduce mental fatigue, increase mental sharpness and increase memory and learning capacity. The first noticeable effect is usually stabilization of mood and general feeling of well-being. 

Selank as an Antiviral Agent 

Selank neuropeptide also expresses immunomodulatory effects. In 2009 a study by F. Ershov et all. has evaluated antiviral properties of Selank both in vitro and in vivo against the influenza virus strain A/Aichi 2/68 (H3N2). The pronounced antiviral effect of Selank was detected in both systems. The highest efficiency - completely supressed viral reproduction was shown when Selank was added to the cell culture 24 hours before inoculation. 

Selank effects 

Improvement of learning and memory processes (reference, reference)
Increased sensory attention
Increased curiosity
Increased mental clarity
Restoration of balance of serotonergic and noradrenergic brain system activity (reference)
Anti-anxiety - inhibition of anxiety (reference)
Antiviral activity with no negative effects (reference)
Psychostimulant, anti-asthenic - increased mental energy (reference)
Stabilization of mood and overall feeling of wellbeing
Reversal of anhedonia (restoring the feeling of pleasure)
Potential restoration of catecholaminergic system functions after damage due to drug abuse reference

High quality peptide powder DSIP/steroidmisty@ycphar.com

Product Name:Delta sleep-inducing peptide,DSIP
CAS NO:62568-57-4
Molecular Formula:C35H48N10O15
Molecular Weight:848.81
Purity:99%
Specification:2mg/vial
Grade:pharmaceutical grade

Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.

DSIP Function

Many roles for DSIP have been suggested following research carried out using peptide analogues with a greater molecular stability and through measuring DSIP-like immunological (DSIP-LI) response by injecting DSIP antiserum and antibodies

Roles in endocrine regulation

Decreases basal corticotropin level and blocks its release.
Stimulates release of luteinizing hormone (LH).
Stimulates release of somatoliberin and somatotrophin secretion and inhibits somatostatin secretion.

Structure and Interactions

DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif:N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C

It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids.[5] In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). It is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.

In vitro it has been found to have a low molecular stability with a half life of only 15 minutes due to the action of a specific aminopeptidase-like enzyme.It has been suggested that in the body it complexes with carrier proteins to prevent degradation, or exists as a component of a large precursor molecule,but as yet no structure or gene has been found for this precursor.

Evidence supports the current belief that it is regulated by glucocorticoids.

Gimble et al. suggest that DSIP interacts with components of the MAPK cascade and is homologous to glucocorticoid-induced leucine zipper (GILZ).GILZ can be induced by Dexamethasone. It prevents Raf-1 activation, which inhibits phosphorylation and activation of ERK.

Roles in Disease and Medicine

Anticarcinogenic
Analgesic effect
Geroprotective effects

Bodybuilding peptide powder Ipamorelin/steroidmisty@ycphar.com

Product Name :Ipamorelin
CAS: 170851-70-4
Molecular Formula: C38H49N9O5
MW:711.853         
Appearance: White powder
Grade : Pharmaceutical Grade
Purity:99%min
Specification:2mg/vial

Ipamorelin is a kind of GHRP

Ipamorelin is a peptidic, selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS) and a growth hormone secretagogue.It is a pentapeptide with the amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2 that was derived from GHRP-1.

Ipamorelin or NNC 26-0161, a polypeptide hormone, is a growth hormone secretagogue and ghrelin mimetic and analog.  Ipamorelin belongs to the most recent generation of GHRPs and causes significant release of growth hormone by itself, due both to its suppression of somatostatin (an antagonist to GHRH) and stimulation of release of GH from the anterior pituitary, similar to GHRP-2 and GHRP-6 which are compounds from the same class (growth hormone releasing peptides).  The cells that produce and release GH are known as somatotropes.   Ipamorelin acts synergistically when applied during a native GHRH (growth-hormone releasing hormone) pulse or when co-administered with GHRH or a GHRH analog such as Sermorelin or GRF 1-29 (growth releasing factor, aminos 1-29).  

The synergy comes both due to the suppression of somatostatin and the fact that ipamorelin increases GH release per-somatotrope, while GHRH increases the number of somatotropes releasing GH.  There is also a secondary effect of neuronal excitation in the hypothalamus caused by ipamorelin, which lasts for approximately 3 hours after application, similar to GHRP-2 and GHRP-6.

Compared to GHRP-2 and GHRP-6

Ipamorelin significantly increases plasma growth hormone (GH) levels in both animals and humans.In addition, ipamorelin stimulates body weight gain in animals.Like pralmorelin and GHRP-6, ipamorelin does not affect prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), or thyroid-stimulating hormone (TSH) levels.

However, unlike pralmorelin (GHRP-2) and GHRP-6, but similarly to growth hormone-releasing hormone (GHRH), ipamorelin does not stimulate the secretion of adrenocorticotropic hormone (ACTH) or cortisol, and is highly selective for inducing the secretion only of GH.

Ipamorelin has a unique property among the GHRP class of peptides.  That property is known as selectiveness.  Whereas GHRP-6 and GHRP-2 cause a release and increase in cortisol and prolactin levels, ipamorelin only selectively releases GH at any dose.  Further, a mega-dose of ipamorelin results in a concomitant mega-release of GH (up to the entire amount present in the pituitary), whereas GHRP-2 and GHRP-6 have limits of approximately 1mcg/kg in humans for their maximal GH release.

Ipamorelin Function

Increased energy 
Improved sleep and mood 
Increased lean muscle mass 
Decreased body fat 
Increased healing ability 
Increased collagen production 
No marked effects on FSH, LH, or TSH plasma levels