High quality peptide powder DSIP/steroidmisty@ycphar.com

Product Name:Delta sleep-inducing peptide,DSIP
CAS NO:62568-57-4
Molecular Formula:C35H48N10O15
Molecular Weight:848.81
Purity:99%
Specification:2mg/vial
Grade:pharmaceutical grade

Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.

DSIP Function

Many roles for DSIP have been suggested following research carried out using peptide analogues with a greater molecular stability and through measuring DSIP-like immunological (DSIP-LI) response by injecting DSIP antiserum and antibodies

Roles in endocrine regulation

Decreases basal corticotropin level and blocks its release.
Stimulates release of luteinizing hormone (LH).
Stimulates release of somatoliberin and somatotrophin secretion and inhibits somatostatin secretion.

Structure and Interactions

DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif:N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C

It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids.[5] In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). It is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.

In vitro it has been found to have a low molecular stability with a half life of only 15 minutes due to the action of a specific aminopeptidase-like enzyme.It has been suggested that in the body it complexes with carrier proteins to prevent degradation, or exists as a component of a large precursor molecule,but as yet no structure or gene has been found for this precursor.

Evidence supports the current belief that it is regulated by glucocorticoids.

Gimble et al. suggest that DSIP interacts with components of the MAPK cascade and is homologous to glucocorticoid-induced leucine zipper (GILZ).GILZ can be induced by Dexamethasone. It prevents Raf-1 activation, which inhibits phosphorylation and activation of ERK.

Roles in Disease and Medicine

Anticarcinogenic
Analgesic effect
Geroprotective effects

High quality peptide powder GHRP-6/steroidmisty@ycphar.com

Product Name:GHRP-6 (Growth hormone releasing peptide)
CAS: 87616-84-0
Molecular Formula: C46H56N12O6
Molecular Weight: 873.01
Purity (HPLC): 98.0%min.
Specifications:5mg/vial,10mg/vial
Appearance: White powder
Grade : Pharmaceutical Grade
Storage: Closed, below 2 ~ 8℃ preservation

General Information

Growth Hormone Releasing Peptide-6 or GHRP-6 is basically a hgH secretagoue, which has the potential to facilitate the effective increase the levels of natural secretion of hgH in our body. At the same time, this compound can also facilitate a sudden increase in body mass and bring about a massive reduction in body fat. GHRP-6 also includes artificial d-amino acids which lead the body to release growth hormones as well. GHRP-6 is not known to work well with GHRH, so it works at the Ghrelin's receptor in place of that receptor.

GHRP-6 is a compound with a unique chain consisting of 6 amino acids which is responsible for telling our body when it has to start releasing the HGH secretions. GHRP-6 also blocks out somatostatin, a hormone which is primarily responsible for stopping HGH secretions from releasing.

The main use of GHRP-6 is promoting food consumption by initiating the feeling of hunger and to improve a person's energy metabolism. This compound has also been extensively used to treat the deficiency of growth hormone along with other complications like cachexia, obesity, and eating disorders.

Although, GHRP-6 is relatively new in the market it has become quite the rage as performance enhancer. It is being made available the market by a few research companies.

How does it work?

GHRP-6 directly stimulates the anterior pituitary gland which subsequently leads to an increase in the release of growth hormones in the body. As GHRP-6 directly affects the feedback loop which triggers changes in inhibition of the release of Growth Hormones, it can be used to restore the natural manufacturing of the Growth Hormone if natural secretion has been impaired because of long term artificial use. GHRP-6 also reportedly has an impact on our nervous system. They are potentially capable of protecting neurons and increasing the strength of a person. The functioning of GHRP-6 is strikingly similar to the working of several steroids in the DHT family. 

Benefits of GHRP-6 

As discussed earlier, GHRP-6 is a newer drug in the market, but it has caught on the fancy of many who are looking for a shortcut to performance enhancement. The following benefits come after GHRP-6 administration:

Lowers body fat: GHRP-6 administration has the reputation of lowering fat, making it a good option for bodybuilders in their cutting cycles. It is also extremely attractive to those people who are weight conscious and are looking to shed those extra pounds without working hard at the gym.
Increase muscle: GHRP-6 administration also has the reputation of facilitating an increase and development in muscles. 
Increase stamina: Those users who are vouching for the drug claim improvement in stamina levels post the administration of GHRP-6.
Protective and anti-inflammatory: GHRP-6 administration initiates better protection of the muscles and acts as an anti-inflammatory agent which is crucial in the muscle recovery process and synthesis. 
GHRP-6 also ensures that the liver is working to initiate IGF-1 secretions helping you lose fat quicker and gain strength as the time passes by.

Dosing and Usage

Despite it being third in class as far as strength of GH release, GHRP-6 is still a potent GHRP and can be taken 2-3 times per day. Though there is a slight issue, GHRP-6 has been shown to not be as effective in the presence of elevated blood glucose levels. As a result, I believe the best practice for GHRP-6 dosing is to dose 2 hours after your last meal and 30 minutes before you take in any food, so that no interactions weaken the effect of GHRP-6. Taking this into consideration, GHRP-6 can be taken 2-3 times a day (approximately 3 hours in between injections) for maximum effectiveness with a range of 100mcg-200mcg per dose.

Bodybuilding peptide powder Melanotan I/Bodybuilding peptide powder

Alias: Melanotan-1, Melanotan I, Afamelanotide, Melanotan, Melanotropin
CAS: 75921-69-6
MF: C78H111N21O19
MW: 1646.845
Purity: 99%
Specification: 10mg/vial
Appearance: White Lyophilized Powder
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be s

tored at 4° C between 2-21 days and for future use below -18° C.

Usage:
Melanotan 1 (also referred to as Afamelanotide) is a synthetic peptide variant of a peptide hormone, called alpha-Melanocyte stimulating hormone or MSH that is naturally produced in the body and is responsible for stimulating melanogenesis, a peptide process for pigmentation of the skin. Alpha-MSH activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan-1 sunless skin tanning effects. While Melanotan 2 and PT-141 have been studied at length as a potential remedies for the treatment of sexual dysfunction, Melanotan-1 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.
Both Melanotan-1 and Melanotan 2 are analogs of the peptide hormone alpha-melanocyte stimulating hormone (α -MSH) that tend to induce skin tanning. Unlike Melanotan 1, Melanotan 2 has been shown to have aphrodisiac properties, the additional effect of increasing libido. Melanotan-1 is a non selective agonist of the melanocortin receptors (MC1R, MC3-5R). As an analogue of α -MSH, its mechanism of action is biomimicry of the natural mammalian tanning process.

Bodybuilding peptide powder Ipamorelin/steroidmisty@ycphar.com

Product Name :Ipamorelin
CAS: 170851-70-4
Molecular Formula: C38H49N9O5
MW:711.853         
Appearance: White powder
Grade : Pharmaceutical Grade
Purity:99%min
Specification:2mg/vial

Ipamorelin is a kind of GHRP

Ipamorelin is a peptidic, selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS) and a growth hormone secretagogue.It is a pentapeptide with the amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2 that was derived from GHRP-1.

Ipamorelin or NNC 26-0161, a polypeptide hormone, is a growth hormone secretagogue and ghrelin mimetic and analog.  Ipamorelin belongs to the most recent generation of GHRPs and causes significant release of growth hormone by itself, due both to its suppression of somatostatin (an antagonist to GHRH) and stimulation of release of GH from the anterior pituitary, similar to GHRP-2 and GHRP-6 which are compounds from the same class (growth hormone releasing peptides).  The cells that produce and release GH are known as somatotropes.   Ipamorelin acts synergistically when applied during a native GHRH (growth-hormone releasing hormone) pulse or when co-administered with GHRH or a GHRH analog such as Sermorelin or GRF 1-29 (growth releasing factor, aminos 1-29).  

The synergy comes both due to the suppression of somatostatin and the fact that ipamorelin increases GH release per-somatotrope, while GHRH increases the number of somatotropes releasing GH.  There is also a secondary effect of neuronal excitation in the hypothalamus caused by ipamorelin, which lasts for approximately 3 hours after application, similar to GHRP-2 and GHRP-6.

Compared to GHRP-2 and GHRP-6

Ipamorelin significantly increases plasma growth hormone (GH) levels in both animals and humans.In addition, ipamorelin stimulates body weight gain in animals.Like pralmorelin and GHRP-6, ipamorelin does not affect prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), or thyroid-stimulating hormone (TSH) levels.

However, unlike pralmorelin (GHRP-2) and GHRP-6, but similarly to growth hormone-releasing hormone (GHRH), ipamorelin does not stimulate the secretion of adrenocorticotropic hormone (ACTH) or cortisol, and is highly selective for inducing the secretion only of GH.

Ipamorelin has a unique property among the GHRP class of peptides.  That property is known as selectiveness.  Whereas GHRP-6 and GHRP-2 cause a release and increase in cortisol and prolactin levels, ipamorelin only selectively releases GH at any dose.  Further, a mega-dose of ipamorelin results in a concomitant mega-release of GH (up to the entire amount present in the pituitary), whereas GHRP-2 and GHRP-6 have limits of approximately 1mcg/kg in humans for their maximal GH release.

Ipamorelin Function

Increased energy 
Improved sleep and mood 
Increased lean muscle mass 
Decreased body fat 
Increased healing ability 
Increased collagen production 
No marked effects on FSH, LH, or TSH plasma levels